After an introduction to ELISAs and micropipettes, students do their own ELISA assays by taking sample "body fluids," one of which is infected (though they don't know which one). Students swap "body fluids" and complete an ELISA to see who became infected and then backtrack to figure out which student was patient zero.

After the lab, the students carry this information into a multi-day case study about the 2014 Ebola outbreak, where they do a digital version of an ELISA and a PCR (polymerase chain reaction).